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Preparative Liquid Chromatography Systems
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CSBio provides users with preparative-HPLC systems and chromatographic columns of different scales. The preparative LC systems we provide can be used for the preparation and separation of fermentation drugs, natural product APIs, peptide drugs, pharmaceutical intermediates and chemical intermediates.
CSBio has added purification equipment to our automated peptide synthesizer product line, enabling us to provide complete services and equipment from peptide synthesis to final purification.
Technical service and after-sales service commitment:
I. Free training plan:
1) Free technical training for personnel and long-term technical support plan;
2) Our company will provide free technical consultation on product performance, use, maintenance, etc.
II. Extra-long warranty:
The free warranty period for the instrument host and main components is 1 year (consumables are not included), and the warranty period is calculated from the date of instrument acceptance signature. During the warranty period, all services and accessories (due to equipment malfunction without human interference) are free of charge, and lifelong maintenance is provided.
III. Quick response:
Our company's maintenance engineers will make a substantive response to the user's service requirements within 4 hours after receiving the notice and provide emergency strategies. If on-site service is required, we can arrive on-site within 24 hours.
IV. Out-of-warranty maintenance:
Outside the warranty period, our company will provide regular maintenance and lifelong maintenance. Our company promises to charge a preferential maintenance fee for on-site maintenance outside the warranty period. If you need to replace spare parts and purchase accessories, it will be provided at cost.
V. System upgrade:
Our company will provide users with free lifetime software upgrades for the instrument, and charge cost-based fees for related hardware upgrades. As well as provide formal upgrade solutions for problems and faults that cannot be solved by maintenance and technical support.
Ⅵ. Spot accessories:
Long-term guarantee of spot supply.
Ⅶ. Regular return visits:
Our company will provide regular return visits to customers (or maintenance and inspection visits), feedback on product usage, and help users solve technical problems related to use and maintenance.
East China Contact: Yawen Lu 18918306841
Southwest China Contact: Yi Shi 18189132222
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Semi-Prep LC System – GL7000 Lab Series, Semi-Prep/Prep LC System[Purification of milligrams to grams]
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GL7000 Semi-Prep SC Series
● Configuration Options:
Flow Rate: 25ml, 50ml, 100ml, 300ml, 500ml max flow rate pump heads
Inner Diameter: 25.4mm, 50mm, 77mm, 100mm SC Preparative Columns
● System performance: routine purification of samples from milligram to gram levels; providing an efficient, economical, and reliable purification platform. Easily transfer analytical chromatography methods to preparative chromatography operating platforms, saving development time and reducing sample and solvent consumption; meeting the development of purification process methods and various application scenarios of semi-preparative and gram-level purification.
● Application areas:Screening of active substances in the research and development of botanical drugs, microbial fermentation drugs, synthetic drugs, etc.; purification of commonly used standard products and alignment products.
A typical configuration is as follows:
GL7000 Semi-Prep DAC Series
● Configuration Options
Flow Rate: 50ml, 100ml, 300ml, 500ml max flow rate pump heads
Inner Diameter: 150mm, 200mm DAC Preparative Columns
● System performance: routine purification of milligram to gram samples, providing an efficient, economical and reliable purification platform; easily transfer analytical chromatography methods to preparative chromatography operation platforms, saving development time and reducing sample and solvent consumption; meeting the development of purification process methods and various application scenarios of semi-preparative and gram-scale purification; widely applicable to various chromatography modes such as normal phase, reverse phase, and ion exchange.
● Application areas:Screening of active substances in the research and development of botanical drugs, microbial fermentation drugs, synthetic drugs, etc.; purification of commonly used standard products and alignment products.
A typical configuration is as follows:
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Pilot Scale Preparative LC System – GL7000 Pilot Scale LC Series [ Purification of grams to hundred grams]
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● System Configuration:
500ml, 1L Max flow rate pump heads (Optional)
ID 150mm, 200mm DAC Preparative Columns (Optional)
● System performance:routine purification of products from grams to hundreds of grams, providing an efficient, economical and reliable purification platform;
Meet the verification and scale-up of liquid chromatography preparation and separation methods for purification processes and small-scale purification;
Widely applicable to various chromatographic modes such as normal phase, reverse phase, and ion exchange;
● Application areas: Production of pharmaceutical products (natural product APIs, peptide protein drugs, fermentation and other synthetic drugs, etc.);
Pharmaceutical intermediates, chemical intermediates and food additives, etc.; large-scale product purification exploration and optimization.
A typical configuration is as follows:
GL7000-1L Pilot Scale Preparative LC System (Configured w/ DAC150)
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No.
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Part No.
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Part Name
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Quantity
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1
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GL7000-1000-01
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GL7000-1000ml/min High-Pressure Infusion Pump (Binary)
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2
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2
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GL7000-1000-02
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UV-3292 UV/Vis Detector; w/ flow cell
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1
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3
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GL7000-1000-03
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ID 150mm DAC Preparative Column
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1
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4
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GL7000-1000-04
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GL7000-1000ml/min High-Pressure Injection Pump
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1
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5
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GL7000-1000-05
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GL7000 Chromatography Software Workstation
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1
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6
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GL7000-1000-06
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GL7000 Fraction Collector (Optional)
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1
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7
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GL7000-1000-07
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Brand Name Computer (Optional)
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1
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8
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GL7000-1000-08
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GL7000 Static Mixer
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1
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9
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GL7000-1000-09
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GL7000 Inline Filter
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1
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10
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GL7000-1000-10
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GL7000 Tool Kit
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1
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Industrial-Prep HPLC Systems
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● System Configuration
2L, 3L, 5L Max flow rate pump heads (Optional)
ID 300mm, 450mm, 600mm DAC Preparative Columns (Optional)
●System performance: Routine purification and separation of products from hundred grams to
kilograms,providing an economical, reliable and efficient production platform;
Widely applicable to various chromatographic modes such as normal phase, reverse phase, ion exchange, etc.
● Application areas: Production of pharmaceutical products (natural product APIs, polypeptide protein
drugs, fermentation and other synthetic drugs, etc.);
Pharmaceutical intermediates, chemical intermediates and food additives industries, etc.
GL7000-2L System Recommended Configuration DAC300
GL7000-3L System Recommended Configuration DAC450
GL7000-5L System Recommended Configuration DAC600
A typical configuration is as follows:
GL7000-2L Industrial Preparative LC System (Configured w/ DAC300)
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No.
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Part No.
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Part Name
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Quantity
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1
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GL7000-2L-01
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GL7000-2L/min High-Pressure Infusion Pump
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2
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2
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GL7000-2L-02
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UV-3292 UV/Vis Detector; w/ flow cell
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1
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3
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GL7000-2L-03
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ID 300mm DAC Preparative Column
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1
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4
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GL7000-2L-04
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GL7000-2L/min High-Pressure Injection Pump
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1
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5
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GL7000-2L-05
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GL7000 Chromatography Software Workstation
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1
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6
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GL7000-2L-06
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GL7000 Fraction Collector (Optional)
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1
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7
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GL7000-2L-07
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Brand Name Computer (Optional)
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1
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8
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GL7000-2L-08
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GL7000 Static Mixer
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1
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9
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GL7000-2L-09
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GL7000 Inline Filter
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1
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10
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GL7000-2L-10
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GL7000 Tool Kit
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1
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Columns
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Spring Preparative LC Columns (SC)
● Application areas:
Suitable for small-scale purification and separation tasks in laboratories of scientific research institutions and pharmaceutical companies, and can be used for routine purification of samples from milligrams to grams.
● Spring column features: 25.4mm, 50mm, 80mm, 100mm specifications of spring preparation chromatographic columns, with internationally advanced axial compression technology, our company has independent intellectual property rights.
1. The international spring adaptive adjustment device design is adopted. When maintaining a stable high internal pressure, the column bed will not collapse, and the column efficiency will not drop sharply. Even if the column bed is loose and collapsed, no tools are required, and the spring column can realize the function of self-stabilizing the column bed;
2. The inner wall of the column barrel adopts military-grade precision polishing and concentric processing technology: the surface roughness of the column wall Ra≤0.2μm. Minimize the influence of the column wall effect, higher product quality and more stable performance;
3. High column efficiency, it is easy to achieve linear amplification from analysis to preparation; the unique column end distribution piece design makes the chromatography process of the sample more uniform and the peak shape more symmetrical;
4. It can be disassembled, which is convenient for users to refill various fillers by themselves. This type of spring column can also be used in both positive and negative directions;
5. The actual use effect is much better than the general fixed flange sealed preparation chromatographic column and other preparation chromatographic columns.
Note: According to customer requirements, we can customize various (special) specifications of empty preparative chromatographic columns or pre-install various fillers such as Kromasil, Daisogel, Fuji, NanoMicro, Huapu, etc., and provide customers with services such as refilling of domestic and imported preparative chromatographic columns.
Dynamic Axial Columns (DAC)
● Application areas:
separation and purification processes in scientific research institutions, pharmaceutical companies from laboratory scale to pilot scale and large-scale production.
● DAC Features: At present, our company's DACs are the most widely used chromatographic column in the field of industrial purification. Generally speaking, when the inner diameter of the chromatographic column is greater than 100 mm, the DAC must be used, and the dynamic axial compression technology is adopted to prevent the bed from collapsing or eliminate the influence of the bed collapse.
1. The adopted structural design has a simple appearance and is flexible and convenient to operate;
2. The piston lifting speed is fast and stable, the liquid flow is evenly distributed, the sealing performance is good, the pressure resistance is high, and the pressure stabilization time is long;
3. The DAC technology applies constant and uninterrupted pressure to the chromatographic column bed, effectively avoiding the collapse of the column head and the loosening of the column bed, and the column efficiency is high;
4. It can meet the needs of long-term use. Once the chromatographic column is contaminated, it is easy and convenient to unload and refill;
5. Overpressure protection is adopted to fully ensure the safety of users;
Note: Our company can also design and customize special specifications and special styles of DAC columns according to customer requirements, and can pre-configure various fillers such as Kromasil, Daisogel, Fuji, NanoMicro, Huapu, etc. according to customer requirements.
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